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From: BAR on 12 Mar 2010 07:31 In article <wclark2-4766D1.20413011032010(a)charm.magnus.acs.ohio- state.edu>, wclark2(a)colnospamumbus.rr.com says... > There we go - the plagiarized cut and paste we all expected. We learned it from you, the master of unattributed cut and pastes from Wikipedia.
From: William Clark on 12 Mar 2010 08:26 In article <3694bdf9-f055-4f76-8eaa-2e390eb63263(a)g4g2000yqa.googlegroups.com>, Dinosaur_Sr <frostback(a)dukesofbiohazard.com> wrote: > On Mar 11, 1:56�pm, "Moderate" <no spam @no mail.com> wrote: > > "MNMikeW" <MNMiik...(a)aol.com> wrote in message > > > > news:7vsl35Fbm3U1(a)mid.individual.net... > > > > > > > > > "BAR" <sc...(a)you.com> wrote in message > > >news:MPG.2602bfb33b80b97b989cd0(a)news.giganews.com... > > >> In article <clark-31F53B.08321411032...(a)charm.magnus.acs.ohio- > > >> state.edu>, cl...(a)nospam.matsceng.ohio-state.edu says... > > > > >>> Out there in public for anyone to look at. > > > > >> Where is the link? > > > > > Clark has something to hide, hence no link. > > > > His MO is to accuse people of the things he is doing. �This comes as no > > surprise. > > In science, the little people always belittle their colleagues. We > have a lot of people who get some job by earning gold stars in the > classroom, but when it comes to actually producing real science, they > just don't have it, and so they justify themselves through the > belittlement of others. We have seen it a couple of times here on RSG. > Doesn't mean much. One's own words describe only one's own self. You have the gall to talk about "belittling" people? My irony meter just exploded.
From: William Clark on 12 Mar 2010 08:27 In article <MPG.2603fe1645d1e633989cd7(a)news.giganews.com>, BAR <screw(a)you.com> wrote: > In article <wclark2-4766D1.20413011032010(a)charm.magnus.acs.ohio- > state.edu>, wclark2(a)colnospamumbus.rr.com says... > > There we go - the plagiarized cut and paste we all expected. > > We learned it from you, the master of unattributed cut and pastes from > Wikipedia. Right. Keep it up, Bertie. Surely someone will side with you.
From: BAR on 12 Mar 2010 08:40 In article <clark-01C165.08274512032010(a)charm.magnus.acs.ohio- state.edu>, clark(a)nospam.matsceng.ohio-state.edu says... > > In article <MPG.2603fe1645d1e633989cd7(a)news.giganews.com>, > BAR <screw(a)you.com> wrote: > > > In article <wclark2-4766D1.20413011032010(a)charm.magnus.acs.ohio- > > state.edu>, wclark2(a)colnospamumbus.rr.com says... > > > There we go - the plagiarized cut and paste we all expected. > > > > We learned it from you, the master of unattributed cut and pastes from > > Wikipedia. > > Right. Keep it up, Bertie. Surely someone will side with you. Do you remember when you used Puerto Rico as an example of universal health care? You did a cut and paste from Wikipedia without attribution. Google is not your friend.
From: Dinosaur_Sr on 12 Mar 2010 09:31
On Mar 11, 4:33 pm, "John B." <johnb...(a)gmail.com> wrote: > On Mar 11, 4:12 pm, Dinosaur_Sr <frostb...(a)dukesofbiohazard.com> > wrote: > > > > > On Mar 11, 2:52 pm, "John B." <johnb...(a)gmail.com> wrote: > > > > On Mar 11, 2:07 pm, Dinosaur_Sr <frostb...(a)dukesofbiohazard.com> > > > > > You really want me to "educate" you on ALS? I can, you know!- Hide quoted text - > > > > > - Show quoted text - > > > > Sure, go ahead and make a fool of yourself, as if you haven't already.. > > > No problem! > > > The symptoms of ALS are caused by oxidative damage to cells, at least > > in the classic sense. With the politics of disease these days, we have > > the Muscular Dystrophy people wanting MD to somehow be associated with > > ALS. Both are diseases caused by progressive cell damage and cell > > death, but totally different causes. ALS is caused by oxidative damage > > to cells. MD is caused by deficiencies in structural proteins in > > muscle cells. > > > Classic ALS is superoxide dismutase deficiency, or SOD deficiency. SOD > > is an enzyme that degrades a molecule that will oxidize other > > molecules in your cell. Oxygen is, as we all know, toxic to your cells > > because it is a powerful oxidant, and the molecules in your cells, > > particularly proteins, are highly reduced. When oxygen, and molecules > > like superoxide, which do come to be in our cells for various reasons, > > are not processed properly, our cells suffer oxidative damage. Classic > > ALS is the accumulation of cell damage due to oxidative stress. People > > whose cells do not process oxidizing agents in their cells properly > > can suffer from diseases like ALS. SOD deficiency, the classic form of > > ALS, is a disease you are born with, and the cell damage accumulates > > over your life and will eventually kill you if you don't die of > > something else first. There are other enzymes involved in removing > > oxidizing agents in your cells, and if any of the genes for those > > enzymes are deficient, you could develop ALS. Of course your > > mitochondria are oxygen vacuum cleaners in your cells, and gobble up > > most of the oxygen that comes into your cells, but when your > > mitochondria don't work well, ALS would be a minor effect in most if > > not all cases! > > > Why ALS though, essentially a degradation of peripheral nerves? The > > more metabolically active cells in your body will suffer damage from > > things like SOD deficiency first. Neurons are pretty much the most > > metabolically active cells in your body, and so the more metabolically > > active nerves will go first. You need peripheral nerves to do things > > like breath, and thus not being able to breath is a major cause of > > death for people with SOD deficiency (also a major cause of death for > > people with MD, but in the case of MD, it is the muscle cells that > > don't work). > > > There are also multifactorial causes of ALS, more than one gene, > > interacting with environmental factors. Tough to pin down directly, > > but they are working on it. > > > They have developed some treatments that can reduce oxidative damage > > to cells, but you have to take them pretty early on for any presumed > > effect. Once the symptoms develop, there is not much you can do. The > > damage is done, and hence the symptoms. But if you had the disease in > > your family history, you could be genetically tested and if you had > > some gene deficiency associated with ALS, you could begin some > > treatments. If it were me, I would. > > > There is evidence of ALS brought on by environmental factors. I am > > personally somewhat suspicious of such claims, as they are usually > > associated with lawsuits. I don't see how some environmental cause > > could attack all your cells like that, or attack just peripheral > > neurons, but some of the arguments are compelling even if lacking in > > direct, empirical cause and effect evidence (as we all know, > > correlation is not indicative of causality!). > > > Trying to be non technical, and I don't want to rant on too > > much...time to take the dogs for a walk anyways. > > > There is a really nice textbook on genetic diseases out there called > > Thompson and Thompson, Genetics in Medicine, 7th edition (don't get > > anything prior to the 6th ed, revised, as they suck), a British book > > to boot, if you want to learn about genetic diseases. Anyone with a > > basic biology background should be able to handle it, which excludes > > you and Clark I suppose. > > I already knew all this and more, having lived with this disease every > day for 9 years. So you've just wasted a lot of time. You asked! I would never have made such a post unsolicited. I wasted 5 minutes, a nice break while grading papers. Mid term grades are due today! |